To help the patient's liver, doctors prescribe him hepatoprotectors - the means that stimulate this organ. If a person needs hepatoprotectors, a list of drugs with proven efficacy helps to understand the long list of drugs, and the pharmaceutical industry in general offers about 200 such drugs.
Hepatoprotectors - indications
Many people consider liver-hepatoprotective drugs to be miraculous, restoring even an organ completely destroyed by alcohol or a virus. Doctors refute this error and call even the best hepatoprotectors for the liver only a means of support - contributing to the self-healing of tissues. One-time reception of the hepatoprotector will not save the liver from the consequences of the disease, food and alcohol excesses - take the drug you need courses. Prescribe drugs of this type should only doctors, otherwise therapy will not bring positive results.
Applying hepatoprotectors, the list of drugs with proven efficacy is presented below, it is necessary to lead a healthy lifestyle - to maintain a diet, to quit smoking and alcohol, to maintain a satisfactory level of health of the digestive and excretory systems that seriously suffer from liver diseases. Hepatoprotectors - list of indications:
- Hepatitis is alcoholic. This disease in the absence of treatment is fraught with the development of cirrhosis. To restore the liver in this case, you need not only take hepatoprotectors, but completely give up alcohol.
- Hepatitis viral chronic type. With any kind of virus - A, B or C, liver degradation occurs, so hepatoprotectors are prescribed along with antiviral drugs.
- Hepatosis of the liver fat. This disease is typical for the leading sedentary lifestyle of people suffering from obesity and diabetes. Hepatoprotectors are prescribed to slow down the degeneration of the liver along with diet and exercise.
- Medicinal hepatitis (primary toxic biliary cirrhosis). In this case, hepatoprotectors are prescribed to reduce the toxic effects of medicines on the liver.
Hepatoprotectors - classification
The type of prescription the doctor determines, based on the patient's condition and the stage of damage to liver tissue. Depending on the main active components, there are the following types of hepatoprotectors:
- essential phospholipids;
- preparations of bile acids;
- on the basis of amino acids;
- animal origin;
- plant origin;
- Supplements.
Essential phospholipids
Drugs of this category are widely used for the treatment of liver diseases. Essential phospholipids are esters that are embedded in the cell membranes and restore their work, normalize the protein and lipid metabolism, stop the process of replacing the liver cells with a connective tissue. These drugs are prohibited for children under 12 years of age and with individual intolerance. Hepatoprotectors - essential phospholipids, a list of drugs with proven efficacy:
- Essentiale N (Essentiale Forte N) - an effective hepatoprotector on soybean phospholipids, is used for toxic or viral liver damage;
- Phospholip - the basis of the drug lecithin, is prescribed for fatty hepatosis, acute intoxication of the body;
- Essel Forte - contains phospholipids, nicotinamide, vitamins, is prescribed for pathologies of the liver and gallbladder.
Preparations of bile acids
Medications for the liver and gallbladder with bile acids are drugs with ursodeoxycholic acid, they are recommended for cholelithiasis, and they are contraindicated in calcium formations in the gallbladder, acute inflammation of the gallbladder:
- Ursofalk , Ursosan - reduce the level of cholesterol, strengthen the membranes of liver cells, promote the dissolution of cholesterol stones in the gallbladder, reduce toxic liver damage;
- Livedoksa - has a cytoprotective effect, immunomodelling action, stimulates the elimination of toxic substances, increases the solubility of cholesterol and reduces the likelihood of the formation of cholesterol stones, neutralizes the effect of toxic bile acids.
Amino acids for the liver
Medicines-hepatoprotectors of this variety are divided into two main groups - with the amino acid ademetionine and the amino acid ornith aspartate. The action of the drugs depends on the main active substance:
- Heptral , heptor - contain ademetionin, this amino acid has a regenerating and antitoxic effect, is prescribed for fatty hepatosis, hepatitis, alcohol poisoning;
- Hepa-Merz - contains ornith aspartate, this amino acid helps to lower the level of ammonia and maintains the capacity of the liver, is prescribed for fat and toxic hepatitis.
Hepatoprotectors of animal origin
Preparations-hepatoprotectors for the liver of animal origin are produced from the components of the liver of livestock. They are used to treat hepatitis, cirrhosis, fatty hepatosis, but are not suitable for the prevention of liver problems. Of the positive aspects of hepatoprotectors of this type, doctors note their high ability to excrete toxins and restore the functions of the organ. The disadvantages of drugs include a high risk of allergies, unproven safety and the risk of developing an immunopathological syndrome.
The best hepatoprotectors for liver of animal origin:
- Sirepar - stimulates liver regeneration, removes toxins, positively influences hematopoiesis and ripening of erythrocytes, improves blood circulation in the liver;
- Hepatosan - being in the intestine, conducts detoxification, then it has a hepatoprotective effect, normalizing the functionality of the liver.
Hepatoprotectors of plant origin
Vegetable hepatoprotectors are an extensive group of drugs for the treatment of the liver. Phytopreparations can stimulate the secretion of bile, remove toxins, accelerate the regeneration process. The most frequent component of plant hepatoprotectors is silymarin, which is made from milk thistle. Here are the most common and effective drugs:
- Karsil - stabilizes the cell membrane of the liver, stopping the release of enzymes and the intake of toxins, improves the process of restoring the organ;
- Gepabene - normalizes the secretion of bile, relieves bile duct spasm, removes toxins, improves liver function;
- Liv 52 - helps restore liver cells and normalize the functioning of the body.
BADA for liver
BADs are herbal preparations, which basically act as prevention. Since serious hepatoprotectors in pregnancy are for the most part contraindicated, women in anticipation of the baby and young children may be prescribed dietary supplements to improve the functioning of the liver. The composition of drugs for the liver is milk thistle and other plant components. Supplements-hepatoprotectors, a list of drugs with proven effectiveness:
- Galstena - is prescribed for chronic pancreatitis and for the normalization of the liver, gallbladder;
- Hepel - relieves inflammation and pain, normalizes the work of the intestines, stimulates the secretion of bile, removes toxins;
- Ovesol - a food supplement based on oats and other plants, has anti-inflammatory, detoxification, choleretic effect;
- Hofitol - a preparation of artichoke, normalizes the protective functions of the liver and the state of tissues, stimulates the outflow of bile, speeds up the secretion of bile and prevents its stagnation, removes toxins ..
Hepatoprotectors with proven efficacy - list
Doctors of many countries still argue on whether there are really effective drugs for liver repair. For those who are looking for effective hepatoprotectors, a list of drugs with proven clinical efficacy:
- Essential phospholipids in combination with interferon preparations are effectively treated against hepatitis C;
- bile acid preparations effectively relieve congestion of bile;
- preparations with amino acids have a positive effect on the liver in case of refusal of alcohol.
Rating of hepatoprotectors
The best hepatoprotectors were checked by doctors to confirm their effectiveness, and it was proved:
- Essentiale N Forte - phospholipids have an average efficiency in hepatosis, alcoholic hepatitis, low - with cirrhosis of the liver;
- Ursofalk, Ursosan - the maximum effectiveness in cirrhosis;
- Heptor, Heptral - an average level of effectiveness for cirrhosis and alcoholic hepatitis ;
- Galstena, Hepel - a low level of effectiveness in hepatitis, cirrhosis, hepatosis.
Application of hepatoprotectors
Doctors believe that drugs-hepatoprotectors are necessary in the presence of certain medical indications. Each particular drug can be useful in one case and is useless or dangerous in another. The doctor must prescribe the medicine, preferably the hepatologist. And all patients with hepatic pathologies should be remembered - a magic remedy for complete restoration of the liver does not exist.