Prothrombin is the norm

Assess that a specialist can tell a completely incomprehensible at first glance blood test, far from medicine a person is very difficult. In fact, each indicator allows you to get a fairly large amount of useful information. For example, prothrombin is a vital protein. Verification of the compliance of prothrombin to the norm is not carried out as often as, for example, a general blood test. This is a rather complicated study, therefore it is prescribed in special cases: with screening studies, blood diseases, problems with coagulability.

What is the norm of prothrombin in the blood?

There are several different analyzes for prothrombin:

  1. Prothrombin by Quique allows you to determine the level of protein activity.
  2. Knowing the prothrombin time, you can determine how many seconds the patient's blood coagulates.
  3. Prothrombin index or abbreviated - PTI is the ratio of normal prothrombin time to the parameters of the patient being examined.
  4. INR is an international normalized ratio - an indicator opposite to the PTI. It shows the ratio of prothrombin time of the patient to the normal value of prothrombin.

The most informative and effective studies are those determining the prothrombin index and prothrombin by Kvik:

  1. The normal value of prothrombin in the blood according to Kwick is in the range from 78 to 142 percent.
  2. The PTI value may vary depending on the sensitivity of the reagents used for the study, but ideally should be 95-105%.

For both men and women, the prothrombin ratio remains the same. Any deviation from the norm is cause for concern. To promote an increase or decrease in the level of prothrombin can be various diseases, some of which poses a serious threat to health.

Because of what the level of prothrombin in the blood is higher than normal?

Too much prothrombin in the blood is a symptom of increased blood clotting . This can provoke such factors:

  1. The production of prothrombin is associated with vitamin K. An increased amount of this protein in the blood indicates an overabundance of the vitamin.
  2. A large amount of prothrombin can be observed in malignant tumors.
  3. Excess of the norm in the analysis of blood for prothrombin is observed in patients in the pre-infarcted state.
  4. Very often the level of the protein jumps during pregnancy. Especially in later terms.
  5. Prothrombin may also increase in patients suffering from liver problems.
  6. Sometimes excess protein is due to the use of Aspirin, hormonal contraceptives, diuretics, corticosteroids, anabolic, laxative drugs.
  7. An increase in thromboembolism prothrombin and polycythaemia.

Why is prothrombin lower than normal?

The decrease in prothrombin on health is also not very good. It is caused by such reasons:

  1. Some liver diseases contribute to an increase in prothrombin, but in acute and chronic forms of hepatitis or cirrhosis the protein decreases.
  2. The prothrombin assay will show a value below the norm if the patient is taking drugs that promote coagulation.
  3. The level of prothrombin decreases with a deficiency of vitamin K. Most often the problem develops against a background of dysbiosis and diseases of the gastrointestinal tract.
  4. The lack of fibrinogen affects the results of the tests negatively. And the deficit can be congenital or acquired.

Normalize the level of prothrombin is possible, but the methods of treatment are better coordinated with a specialist. The treatment course depends on the cause of the problem. In most cases, the patient is offered a special diet. Often, for recovery requires special medications.