Because of the high price, intolerance, the appearance of pronounced side effects or increased sensitivity to the components, patients are often asked to replace something with Cerebrolysin - analogues are usually cheaper and better tolerated. But when choosing a drug, many other nuances should be considered and first consult a doctor.
Cerebrolysin analogues in tablets and other oral dosage forms
It should immediately be noted that there are no direct analogues of the described drug according to its active substance (hydrolyzate from the pig's brain tissue). Consider the closest to Cerebrolysin generics, which produce an identical effect.
The best synonymous nootropic in the form of tablets is Actovegin . It is also based on a natural active ingredient - gemoderivate from calf blood after thorough purification (deproteinization).
Actovegin acts as follows:
- normalizes metabolism in brain cells;
- improves the balance of energy in the tissue;
- increases oxygen consumption, preventing hypoxia;
- increases the utilization of sugar by cells;
- reduces manifestations of polyneuropathy;
- reduces the severity of sensitivity disorders;
- helps restore mental stability.
Another analogue of Cerebrolysin is Ceraxon. It is available in several dosage forms, one of which is a solution for internal administration.
Ceraxon is based on sodium citicoline, which has a wide range of effects:
- restores even severely damaged cell membranes;
- prevents the formation of excess amounts of free radicals;
- prevents premature death of active neurons;
- inhibits the functions of phospholipases;
- increases the intensity of cholinergic transmission;
- reduces the extent of brain damage during a stroke;
- reduces the severity of neurological manifestations and the duration of coma after mechanical trauma to the brain;
- shortens the recovery period;
- allows to increase the effectiveness of therapy of cognitive disorders;
- increases the ability to concentrate attention;
- reduces the severity of amnesia .
Synonyms and analogues of Cerebrolysin for intravenous and intramuscular administration
One of the most potent medicines of the type described is Cortexin. It is sold in the form of a powder (lyophilizate) for the subsequent preparation of the solution.
The active substance in Cortexin is a homogeneous complex of polypeptides with very low molecular weight soluble in water. The presented analog of Cerebrolysin is used to perform injections that have a neuroprotective, tissue-specific, nootropic and antioxidant effect.
Cortexin is much more effective in this:
- reduces the toxic effect on brain cells of psychotropic compounds and neurogenic factors;
- activates reparative processes, metabolism of neurons;
- increases the tone of the nervous system;
- improves the functioning of the cerebral cortex;
- intensifies higher cerebral functions;
- increases the resistance of neurons to adverse external influences, as well as their survival;
- contributes to the restoration of cognitive functions of neurons.
Very similar to the mechanism of action of the analogue of Cerebrolysin in ampoules is the already mentioned Ceraxon. It is also available in the form of a solution for intravenous and intramuscular administration, having the same properties as oral fluid. Only in this case, Ceraxon is quickly absorbed, and sodium citicoline immediately enters the brain cells through the circulatory system.