Various dyspeptic disorders are often accompanied by vomiting, which is usually recommended for this remedy. But this drug is used not only to combat this symptom, for diagnostic purposes, in the X-ray study, too, is prescribed Metoclopramide - the indications for the use of the drug are quite extensive, they include even diseases of the endocrine and central nervous system.
What helps these pills and injections of metoclopramide?
The presented drug refers to antiemetics. When ingested in the gastrointestinal tract, this chemical compound increases the tone of the lower sphincter and simultaneously reduces the motor activity of the esophagus. Also, Metoclopramide helps to accelerate the evacuation of stomach contents and its progression through the small intestine. This does not increase the secretion of digestive secretions and there is no diarrhea.
Interestingly, the side effects of the medication make it possible to use it in migraine therapy. In addition, the drug helps healing ulcers on the mucosa of the duodenum and stomach, increases the level of the hormone prolactin.
Indications for Metoclopramide
The following tablets and solution are prescribed for the following pathologies:
- hiccups of different origin;
- nausea;
- vomiting, including - due to the use of cytostatic drugs and after radiation therapy;
- postoperative hypotension of the intestine and stomach;
- flatulence;
- dyskinesia of bile ducts of hypomotor form;
- atony of the stomach and intestines;
- functional stenosis of the esophagus pylorus;
- reflux esophagitis ;
- peptic ulcer of the duodenum, stomach, only as part of an integrated approach;
- functional digestive disorders;
- paresis of the stomach, if it is caused by exacerbation of diabetes mellitus;
- dyspepsia in patients with severe cardiac diseases (heart failure, condition after myocardial infarction);
- attacks of migraine (both in combination with analgesics, and as an independent drug).
Also, metoclopramide was used in performing X-ray studies of the gastrointestinal tract with the administration of contrast media. To accelerate the emptying of the stomach, it is recommended to drink before duodenal gastric intubation. This allows you to improve visibility and makes the procedure more informative.
Indications for the use of injections Metoclopramide are similar to the tablet form. Solution for injection is preferred if the vomiting is so strong that the capsules do not stay in the esophagus and stomach and the active substance does not have time to act.
Dosage of metoclopramide
In the form of tablets, the drug should be taken 3 times a day, about half an hour before the start of the meal, 10 mg (1 capsule).
If the medicine is used for diagnostic purposes, its single administration is prescribed for 5-10 minutes before the beginning of the study in a concentration of 10-20 mg.
Metoclopramide in ampoules in the form of a solution for injection is used in a dosage of 10-20 mg intramuscularly or intravenously, 3 times a day. At the same time, the maximum amount of a drug that can be administered within 24 hours should not exceed 60 mg.
During therapy with cytostatic medications or performing irradiation, Metoclopramide is used intravenously at the rate of 2 mg of the active ingredient per 10 kg of body weight of the patient. The injection should be done 30 minutes before the procedure, repeat after 2-3 hours.