In order to carry out constant monitoring of the woman's condition, doctors monthly assign several tests - some studies are done only once, others are scheduled for delivery on a monthly basis. One such study is a blood test for D-dimer in pregnancy, which helps determine its level and identify the presence or absence of blood clots to prevent thrombosis, and, consequently, the clogging of veins. With a negative test result, the doctor excludes thrombosis. If the result is positive, additional studies are performed to find a possible cause. For timely diagnosis and prevention of thromboembolism and DIC (syndrome of vascular coagulation), it is necessary to test for D-dimer each woman during pregnancy.
What is a D-dimer?
Many women do not even know where the D-dimer comes from or what it is. Doctors explain: in order to prevent such diseases as the appearance of vein thrombosis, kidney disease, diabetes and pulmonary embolism, it is necessary to take an analysis to the level of D-dimer in pregnancy.
Under the influence of thrombin during the coagulation of blood fibrin is formed, which, dissolving in the plasma, binds to the walls of the vessels. When the fibrin is cleaved, D-dimers are formed in pregnant women. Analysis of D-dimer in pregnancy is always used to study the coagulogram, since it is formed in the body only under the condition of the origin of these two processes.
D-dimer in pregnancy is a protein enzyme that forms during the dissolution of a blood clot that occurs when blood is clotted. These fragments of fibrin cleavage, according to the results of a blood test, can determine the risk of thrombosis. The lifetime of D-dimers is not more than 6 hours.
Analysis of D-dimer in pregnancy
The detection of D-dimer levels in the planning of pregnancy is very important, since its deviation from normal is dangerous for a pregnant woman and fetus and is fraught with diseases such as preeclampsia and gestosis . If his indicator in the blood of a future mom is increased - it means that the blood is thick, and it can form microthrombi, clogging the capillaries, resulting in impaired blood circulation in the uterus. The earlier a deviation is detected, the easier it will be to avoid complications.
Immunoturbidimetry is a method of quantitative detection of D-dimer. In order to properly prepare for the study you need:
- Do not eat fatty foods 24 hours before the test;
- To exclude emotional and physical overstrain for half an hour before the analysis;
- do not smoke before giving blood 30 minutes.
D-dimer - what is the norm during pregnancy?
The norm of the D-dimer index in the blood during pregnancy should not be higher than 248 ng / ml. During the "interesting" position of a woman, this indicator may increase by three or even four times the norm. A high index of D-dimer in pregnancy is permissible. This is due to the fact that significant changes occur in the hemostatic system due to the physiological activation of the clotting process.
It is believed that in the first trimester, the level of D-dimer increases by one and a half times, in the second trimester, as in the third trimester - three times (not more than 1500 ng / ml), compared to the normal level. We indicate the maximum values, so if the D-dimer (d-dimer) indices are low or low in pregnancy, relative to the norm, do not worry.
D-dimer in pregnancy IVF
It should be noted that the drugs prescribed during IVF stimulate the growth of D-dimer in pregnancy. Therefore, it is necessary during the IVF procedure to check the hemostasis in the blood of a pregnant woman.