Lasix is a drug that is characterized by a powerful, fast-paced action. Prescribes the drug with caution, and its application without the recommendation of a specialist is highly undesirable. Let's consider, what indications to application and contra-indications of preparation Lasix.
Composition, form of Lasix
Lasix is a diuretic (diuretic), the main active ingredient of which is a synthetic compound of furosemide. The drug is given in the form of tablets for oral administration, as well as a solution for injections in ampoules.
Pharmacological action of the drug Lasix
Under the influence of the active substance of the drug, certain parts of the kidneys are affected, as a result of which the absorption of sodium and chlorine ions is blocked. At the same time, the absorption of potassium molecules is inhibited. As a result, there is an increase in the formation and excretion of urine, along with which calcium and magnesium ions are actively excreted from the body.
In addition, the use of Lasix increases the lumen of some vessels. In turn, this, together with the removal of excess fluid from the body, causes a reduction in blood pressure. However, this effect with a single administration of the drug is poorly expressed.
When using the injectable solution of Lasix, its effect is observed after about 20-30 minutes, the duration of the therapeutic effect is approximately 3 hours. After oral administration of the drug, the desired effect is achieved after 30 to 50 minutes and lasts approximately 4 hours. The medicine is withdrawn practically unchanged mainly through the kidneys.
Indications for Lasix appointment
Consider what is recommended to take Lasix tablets, as well as injectable drug administration. The main indications are:
- edematous syndrome on the background of chronic heart failure ;
- chronic renal failure accompanied by swelling;
- nephrotic syndrome;
- liver disease with edematous syndrome;
- cerebral edema;
- arterial hypertension (in case of severe course);
- hypertensive crisis;
- the need for forced diuresis for poisoning with certain chemicals.
How to use Lasix?
In most cases, Lasix is prescribed in the form of tablets. However, if oral administration is not possible (for example, if the absorption of the drug in the small intestine is impaired), or if there is a need to obtain the fastest effect, the drug is administered intravenously. Intramuscular Lasix injections are used in very rare cases.
When administering this medication, it is recommended to use its lowest doses, which will be sufficient to achieve the desired therapeutic effect. The dosage, the frequency of administration and the duration of the treatment course depend on the diagnosis and severity of the pathological process.
Contraindications to the use of Lasix:
- anuria on the background of renal failure;
- hepatic coma, precoma;
- potassium deficiency in the body;
- reduced volume of circulating blood;
- dehydration of the body;
- disturbances of outflow of urine;
- intoxication with cardiac glycosides;
- acute glomerulonephritis;
- increased uric acid in the blood;
- increased central venous pressure;
- decompensated aortic and mitral stenosis;
- obstructive form of hypertrophic cardiomyopathy;
- hypersensitivity to the components of the drug, as well as allergy to sulfonamides (possible cross-allergy to furosemide);
- period of pregnancy and lactation.