Duphaston: hormonal or not?

Since Dufaston is now widely used for the treatment of various diseases and pathological conditions associated with hormonal imbalance, women have a legitimate question whether this drug is hormonal with all the ensuing consequences. That is, does it have the side effects of drugs based on hormones.

To answer the question of whether Dufaston tablets are hormonal or not, it is necessary to know what active substance is at its base.

Active substance

The main active substance of Dufaston is dydrogesterone, which is close to natural progesterone. It is a synthetic substitute for progesterone, but it does not come from a male hormone, which explains why it does not have the anabolic, androgenic, estrogenic and thermogenic effects that are characteristic of most drugs based on synthetic hormones.

In this regard, the drug has a minimal set of side effects. Dufaston helps prevent the development of endometrial tumors, has no contraceptive effect, does not disrupt the menstrual cycle. At the time of taking the drug, conception is possible. With hormonal failure, Duphaston helps stabilize the impaired menstrual cycle and make up for the lack of the hormone progesterone.

Contraindications

But, in spite of all the advantages available for this remedy, it is still a hormonal drug, which should be used with great care. The appointment of Dufaston without conducting a thorough examination, "just in case" is unacceptable. After all, after such intervention in the female reproductive system, hormonal failure may occur. Therefore, the use of Dufaston should be justified and only after the diagnosis is made.

The drug can be prescribed for the treatment of diseases such as endometriosis, infertility, dysmenorrhea, premenstrual syndrome, amenorrhea, dysfunctional uterine bleeding , irregular cycle. It should be remembered that despite the fact that the instruction refers to the possibility of using Dufaston during pregnancy, there have been no reliable studies concerning the effect of taking the drug on the fetus.

Do not take the drug and in the presence of intolerance to dydrogesterone, Rotor and Dabin-Johnson syndromes.