Pregnancy will not occur if a woman does not have ovulation. And to make it happen - it is necessary to stimulate ovulation, as a rule, medically. The most common drug in this case is Klostilbegit (international name Klomifen). Klostilbegit - a pill to stimulate ovulation, which are prescribed for irregular ovulation, its absence, polycystic ovaries. The dosage is determined by the doctor after a thorough examination. The drug is aimed at two types of hormones:
- FSH (follicle-stimulating hormone) - affects the preparation of the ovaries mature follicle (follicles);
- LH (luteinizing hormone) - affects the release of the egg from the follicle.
Scheme of ovulation stimulation by Klostilbegit
Clostilbegit begins to take on the fifth day of the menstrual cycle. Take it 1 tablet before bedtime until 9 days. After the end of taking the tablets, the doctor starts to do ultrasound and continues until the follicles reach a size of 20-25 mm. After this, an injection of hCG (human chorionic gonadotropin) is prescribed. It is done once in a dosage determined by a doctor (5000-10000 IU). After 24 hours, at most 36 hours, ovulation occurs. These days the sex life should be active. When ultrasound confirms the onset of ovulation, prescribe progesterone preparations, for example, Dufaston, Utrozestan, Progesterone in ampoules.
Women are usually enough to start regular ovulation 1-2 courses of treatment with Klostilbegitom. If after 3 courses with a gradual increase in dosage, ovulation does not recover, it is necessary to conduct a more thorough examination and review the treatment. It is not necessary to abuse this medicine (it is not recommended to take it more than 5-6 times in life), as this can lead to exhaustion of the ovaries. After that, normal pregnancy will become impossible. It should also be noted that Clostilbegit negatively affects the growth of the endometrium, it is not prescribed for women with an endometrium thinner than 8 mm. In such cases, it is recommended to choose other drugs that stimulate ovulation, such as Puregon, Gonal, Menogon, or others.
Medicamental stimulation of ovulation - to be or not to be?
It is impossible not to mention the side effects of Klostilbegit (as well as many other drugs for the treatment of anovulation). These can be disorders of the central nervous system (mood swings, insomnia, irritability, depression, headache), digestive tract and metabolism (nausea, vomiting, weight gain). Allergic reactions are also possible.
However, with all the shortcomings, we can not fail to say about the merits. Ovulation is completely restored in 70% of women during three cycles of treatment. Of those who were helped by the stimulation of ovulation in 15-50% pregnancy occurs. Data is so different due to the impact
Klostilbegit can stimulate the production of several eggs at once. This property is often used before IVF (in vitro fertilization). With natural fertilization, a multiple pregnancy is possible. For women who stimulate ovulation with Klostilbegit, the probability of twinning is 7%, and triplets - 0.5%.
It is important to remember that taking such medications yourself is unacceptable, treatment should be carried out only under the supervision of a doctor! And when choosing them, it is necessary to take into account the positive and negative properties of the drug, the physiological characteristics and the state of health of women.