Modern non-steroidal anti-inflammatory drugs occupy one of the places of honor in medicine. They have an analgesic and antipyretic effect, quickly remove puffiness, stop inflammation and reduce pain syndromes. Due to these properties they are widely used for the treatment of many diseases.
Indications for use of non-steroidal anti-inflammatory drugs
Modern NSAIDs are available in the form of injections, suppositories, tablets, capsules, gels and ointments. They are usually used for chronic or acute diseases, which are accompanied by severe pain and inflammation. Most often they are prescribed for:
- osteoarthritis;
- gout;
- rheumatoid arthritis;
- Reiter's syndrome ;
- dysmenorrhea;
- migraines and headache;
- metastases of bones;
- fever;
- postoperative pain syndrome;
- renal colic.
Nonsteroid preparations of new generation
Classical nonsteroidal preparations suppressively acted on isoforms of cyclooxygenase: protection enzyme (COX-1) and inflammation enzyme (COX-2). The enzyme of protection was suppressed by them, which provoked a decrease in the protective functions of the mucous membranes of the stomach and various diseases of the whole gastrointestinal tract arose. But non-steroidal anti-inflammatory drugs of the new generation act on the contrary - the enzyme of inflammation is suppressed to a greater degree. Thereby:
- immunity of the body in the process of treatment is stronger;
- side effects occur much less;
- the drug acts more efficiently.
Nonsteroid preparations of the new generation practically do not affect COX-1. All of them are distinguished by a high level of safety for the human body. Some side effects after their use can still occur. But this is only observed if the intake of the newest non-steroidal anti-inflammatory drugs is very long. In this case, they should not be canceled. In some cases, you only need to choose the optimal dose.
What medicines are related to modern non-steroid drugs?
Oksikam - derivatives of non-steroidal drugs. This group of drugs is characterized by an increased half-life. Due to this, the action of the drug in the body is prolonged, which allows reducing the frequency of taking medications. Oksikamy were taken as a basis for the development of modern non-steroid drugs.
An example of a new generation of NSAIDs is Xefokam. This drug has a high analgesic ability. His strength of action can be compared to Morphine. That's just an opiate-like effect on the central nervous system and addictive it does not cause.
Also new non-steroidal anti-inflammatory drugs are:
- Nimesulide - used to treat arthritis and vertebrogenic back pain. After its administration, inflammation disappears, hyperemia, the temperature normalizes, and the mobility improves.
- Celecoxib is a medicine that alleviates the condition of a patient with arthrosis and osteochondrosis. Effectively fights against inflammation and
perfectly removes the pain syndrome. - Meloksikam - a drug that has antipyretic, anti-inflammatory and well-marked analgesic effect. It can be taken even for a long time. It is produced by Meloxicam in the form of tablets, solution for injections, ointments and suppositories.
The only drawback of new nonsteroid drugs is that they do not lead to complete recovery in osteochondrosis, arthrosis of joints and arthritis . In the treatment of these diseases, they are necessary only for relief of pain and / or removal of inflammation.