Thrombophilia is a disturbance of the state of the circulatory system, and arises from pathological changes in the composition and properties of the blood. This disease leads most often to thromboembolism of venous vessels, thrombosis of different localization. Most of all people are susceptible to disease after surgery, during pregnancy, as a consequence of physical overstrain or trauma. If suspected of tobobylia, you need to take a blood test from the vein and, as usual, on an empty stomach.
What causes thrombophilia?
This disease can have an acquired character, which is reflected in defects in the blood coagulation system or in the pathology of cells. And also the cause of thrombophilia can be malignant neoplasms.
However, an analysis for genetic thrombophilia up to 50% of cases gives a positive result. This indicates a hereditary predisposition to the development of thrombosis in most patients. Such a pathology can be caused by genetic disorders and mutations in the blood coagulation and anticoagulation system.
What is an analysis for thrombophilia?
To date, the most informative is the blood test for thrombophilia. With this disease, a blood test shows an increased number of platelets and red blood cells. The volume of erythrocytes increases with respect to the volume of blood.
The blood level is determined by the level of substance, which contributes to the destruction of thrombi, which is called D-dimer. With thrombophilia, its amount increases.
Evaluation of blood clotting activity is carried out due to the analysis determining APTT (activated partial thromboplastin time). This disease is characterized by a decrease in APTT.
Special preparation for analysis for genetic thrombophilia is not required, blood sampling is performed in the regular mode with the patient's habitual lifestyle.