Creatinine is excreted by the kidneys and is the final product of protein metabolism. Knowing the amount of this substance in the body, you can judge the state of the kidneys, their functionality. There is always a reason for raising and lowering creatinine. Often the deviation of the level of matter from the norm is a sign of various diseases and pathological changes.
Causes of a decrease in creatinine in the blood
Specialists have established a special framework. So, for example, if the blood contains 44 to 80 μmol / L of creatinine, this is considered quite normal. Deviations from the norm are observed quite often. But in most cases, experts have to deal with the increase in the amount of matter.
Reduced creatinine is quite a rare. This phenomenon is evidenced by the fact that metabolism and protein metabolism are disturbed in the body. And this, in turn, is fraught with depletion of the body's energy reserves, which can have very unpleasant consequences.
Such factors can contribute to a decrease in creatinine:
- chronic diseases;
- starvation;
- muscle diseases leading to their dystrophy;
- a sharp decrease in the muscle mass of a person;
- problems in the work of the kidneys;
- rhabdomyolysis;
- malignant tumors;
- dehydration ;
- injury of muscles and surrounding tissues;
- deficiency of antidiuretic hormone in the body;
- heart failure ;
- cirrhosis and other liver diseases;
- cachexia caused by starvation and disease.
Very often, lowered creatinine is diagnosed in a blood test of pregnant women. Especially during the first trimester of pregnancy. Develop hypocreatinemia and the use of glucocorticoids. Sometimes the body is depleted because of the discrepancy between the physical loads received and nutrition, which is mainly affected by novice amateur athletes.