Citramon is one of the most popular medicines, which many are stored in a home medicine cabinet. This tool is highly effective at a relatively low cost.
Citramon - composition and mechanism of action
In Soviet times, the combination Citramon included a set of the following substances: 0.24 g of acetylsalicylic acid, 0.18 g of phenacetin, 0.015 g of cocoa powder, 0.02 g of citric acid. Today, phenacetin is not used because of toxicity, and new drugs, produced under the names with the word "Citramon", are produced by a large number of pharmaceutical companies.
Most of these drugs have a composition, the main active ingredients of which are:
- Acetylsalicylic acid - has antipyretic and anti-inflammatory effect, promotes anesthesia, moderately inhibits platelet aggregation and thrombosis, improves microcirculation in inflammatory foci;
- Paracetamol - has analgesic, antipyretic and weak anti-inflammatory effect, which is due to its effect on the thermoregulation center and the ability to inhibit the synthesis of prostaglandins in peripheral tissues;
- Caffeine - promotes the expansion of blood vessels, increases the reflex excitability of the spinal cord, excites the respiratory and vasomotor centers, reduces platelet aggregation, reduces the feeling of fatigue and drowsiness.
Modern variants of Citramon differ in the concentration of active substances and in the input auxiliary components, but are characterized by a similar effect. Consider the composition of some drugs:
Citramon-M
Main cast:
- 0.24 g of acetylsalicylic acid;
- 0.18 g of paracetamol;
- 0.03 g of caffeine.
Other components:
- lemon acid;
- starch;
- ascorbic acid;
- calcium stearate;
- cocoa;
- low molecular weight polyvinylpyrolidone.
Citramon-P
Main cast:
- 0.24 g of acetylsalicylic acid;
- 0.18 g of paracetamol;
- 0.03 g of caffeine.
Other components:
- lemon acid;
- calcium stearate;
- talc;
- cocoa;
- starch.
Citramon forte
Main cast:
- 0.32 g of acetylsalicylic acid;
- 0.24 g of paracetamol;
- 0.04 g of caffeine.
Other components:
- lemon acid;
- starch;
- polyvinylpyrolidone low molecular weight medical;
- sodium croscarmellose;
- magnesium stearate;
- cocoa.
Indications for the use of Citramon
According to the instructions for the use of Citramon M, Citramon P and other analogs, they have such indications:
- Pain syndrome of various origin of mild to moderate severity (headache, migraine , neuralgia, myalgia, toothache, arthralgia, etc.);
- Feverish syndrome with influenza, acute respiratory infections and other infectious diseases.
Citramon is a method of application
Citramon is taken during or after a meal, washed down with water, in a dosage of 1 tablet once or 2 to 3 times a day at intervals of not less than 4 hours. The course of taking the drug - no more than 10 days. Do not take Citramon without prescribing and seeing a doctor for more than 5 days for anesthesia and more than 3 days for lowering body temperature.
The use of citramone in pregnancy has its own characteristics. Citramon is contraindicated in the first and third trimester of pregnancy, as well as during lactation. This is due to the negative effects of acetylsalicylic acid (especially in combination with caffeine) on fetal development, as well as the risk of weakening labor, bleeding and premature closure of the aortic duct in the child.
Citramon - contraindications
In addition to pregnancy and lactation, the drug is not recommended for:
- erosions and ulcers of the gastrointestinal tract in the phase of exacerbation;
- hemophilia;
- hemorrhagic diathesis;
- hypoprothrombinemia;
- portal hypertension;
- renal failure ;
- severe arterial hypertension;
- glaucoma;
- increased excitability;
- hypersensitivity to the components of the drug, etc.